False Positive (Trojan.Gen.2) for executable on college training cd's

I have endusers in my HR department who peform training sessions with reputable vendor-supplied disks provided by a local community college. As of last week, they've always been able to run the executable on the training disks for their classes, but suddenly this week the executable is flagged by SEP as a Trojan.Gen.2 risk and prevented from running. Since this executable is on a cd, I can't add it to the Exceptions List. I tried adding a shortcut to the enduser's desktop, then adding the shortcut to the Exceptions List, but this does not work and the executable on the disk continues to be flagged as a threat.  (D:\ACDC.exe is the path/executable that is flagged as a trojan)

Any help would be greatly appreciated.