SEP Virus Defs still saying out of date

The server was low on disk space so the virus defs would not update.  NetOps made space so now SEP shows the virus defs up to date.  But the message still pops up saying that the virus defs are not updated.

Before, I figured out it was a disk space issue, I tried following the documents to manually update by cleaning the directory and registry thinking maybe the virus defs were corrupted.

Any suggestions. 

Thanks. M.